Proper development of a baby depends on the number and structure of microscopic chromosomes. Scientists have identified many abnormalities that occur in these important carriers of our genetic information. Since development relies on the chromosomes, chromosomal abnormalities often result in miscarriage. Though scientists have identified many abnormalities, they are not yet able to determine their cause.
Normal Cells and Chromosomes
Our body is made up of tiny cells, which are constantly replenishing. The chromosomes, which sit inside the nucleus (center) of the cell, are the structures that carry the genetic information that determines each of our individual characteristics from hair color to body structure. There are 46 chromosomes in most cells. The cells of the male sperm and the female egg are unique in their number of chromosomes. At the time of fertilization, they each generally contain 23. Thus, when fertilization occurs, the sperm and egg share their genetic information, giving the resulting embryo 46 chromosomes per cell.
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